Combined influence of genetic and environmental factors in age of rheumatoid arthritis onset. Rodríguez-Rodríguez L, Lamas JR, Varadé J, Tornero-Esteban P, Abasolo L, de la Concha EG, Jover JA, Urcelay E, Fernández-Gutiérrez B. Rheumatol Int. 2011 Sep 16. [Epub ahead of print]. PMID:21922340
Plasma soluble IL-6 receptor concentration in rheumatoid arthritis: associations with the rs8192284 IL6R polymorphism and with disease activity. Rodríguez-Rodríguez L, Lamas JR, Varadé J, López-Romero P, Tornero-Esteban P, Abasolo L, de la Concha EG, Jover JA, Urcelay E, Fernández-Gutiérrez B. Rheumatol Int. 2011 Mar;31(3):409-13. Epub 2010 Jul 27. PMID: 20661738
Study of chromosomal region 5p13.1 in Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Perdigones N, Martín E, Robledo G, Lamas JR, Taxonera C, Díaz-Rubio M, de la Concha EG, López-Nevot MA, García A, Gómez-García M, Fernández-Gutiérrez B, Martín J, Urcelay E. Hum Immunol. 2010 May 16. [Epub ahead of print]. PMID: 20561984
Influence of IL6R rs8192284 Polymorphism Status in Disease Activity in Rheumatoid Arthritis. Lamas JR, Rodríguez-Rodríguez L, Varadé J, López-Romero P, Tornero-Esteban P, Abasolo L, Urcelay E, Fernández-Gutiérrez B. J Rheumatol. 2010 Jun 15. [Epub ahead of print]. PMID: 20551110
Large-scale gene expression in bone marrow mesenchymal stem cells: a putative role for COL10A1 in osteoarthritis. Lamas JR, Rodríguez-Rodríguez L, Vigo AG, Alvarez-Lafuente R, López-Romero P, Marco F, Camafeita E, Dopazo A, Callejas S, Villafuertes E, Hoyas JA, Tornero-Esteban MP, Urcelay E, Fernández-Gutiérrez B. Ann Rheum Dis. 2010 May 24. [Epub ahead of print]. PMID: 20498197
Association study of Ghrelin Receptor gene polymorphisms in Rheumatoid Arthritis. Robledo G, Rueda B, Gonzalez-Gay MA, Fernandez B, Lamas JR, Balsa A, Pascual-Salcedo D, García A, Raya E, Martin J. Clin Exp Rheumatol. 2010 Jan-Feb;28(1):25-9. PMID: 20346234
Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis. Perdigones N, Vigo AG, Lamas JR, Martínez A, Balsa A, Pascual-Salcedo D, de la Concha EG, Fernández-Gutiérrez B, Urcelay E. Arthritis Rheum. 2010 Mar;62(3):705-10.
NO role of NOS2A susceptibility polymorphisms in rheumatoid arthritis. Varadé J, Lamas JR, Fernández-Arquero M, Jover JA, de la Concha EG, Martínez A, Fernández-Gutierrez B, Urcelay E. Nitric Oxide. 2009 Jul 25. [Epub ahead of print] PMID: 19635578
Lack of association with rheumatoid arthritis of selected polymorphisms in 4 candidate genes: CFH, CD209, eotaxin-3, and MHC2TA. Dieguez-Gonzalez R, Akar S, Calaza M, Gonzalez-Alvaro I, Fernandez-Gutierrez B, Lamas JR, de la Serna AR, Caliz R, Blanco FJ, Pascual-Salcedo D, Velloso ML, Perez-Pampin E, Pablos JL, Navarro F, Narvaez J, Lopez-Longo FJ, Herrero-Beaumont G, Gomez-Reino JJ, Gonzalez A. J Rheumatol. 2009 Aug;36(8):1590-5. Epub 2009 Jun 30. PMID: 19567623
Shared epitope and anti-cyclic citrullinated peptide antibodies: relationship with age at onset and duration of disease in rheumatoid arthritis. Varadé J, Loza-Santamaría E, Fernández-Arquero M, Lamas JR, de Los Angeles Figueredo M, Jover JA, de la Concha EG, Rodríguez L, Urcelay E, Fernández-Gutiérrez B, Martínez-Doncel A. J Rheumatol. 2009 May;36(5):1085-6. PMID: 19435975
Lack of association between STAT4 gene polymorphism and biopsy-proven giant cell arteritis. Palomino-Morales R, Vazquez-Rodriguez TR, Morado IC, Castañeda S, Ortego-Centeno N, Miranda-Filloy JA, Lamas JR, Martin J, Gonzalez-Gay MA. J Rheumatol. 2009 May;36(5):1021-5. Epub 2009 Mar 30. PMID: 19332627
6q23 polymorphisms in rheumatoid arthritis Spanish patients. Perdigones N, Lamas JR, Vigo AG, de la Concha EG, Jover JA, Urcelay E, Gutiérrez BF, Martínez A. Rheumatology (Oxford). 2009 Jun;48(6):618-21. Epub 2009 Mar 25. PMID: 19321514
Chromosomal region 16p13: further evidence of increased predisposition to immune diseases. Martínez A, Perdigones N, Cénit M, Espino L, Varadé J, Lamas JR, Santiago JL, Fernández-Arquero M, de la Calle H, Arroyo R, de la Concha EG, Fernandez-Gutierrez B, Urcelay E. Ann Rheum Dis. 2009 Feb 23. [Epub ahead of print] PMID: 19221398
Proteomics: New insights into rheumatic diseases (Review).
Emilio Camafeita, José Ramón Lamas, Enrique Calvo, Juan Antonio López and Benjamín Fernández-Gutiérrez. Proteomics Clin. Appl. 2009, 3, 226–241
GDF5 Polymorphism associated with osteoarthritis: risk for rheumatoid arthritis. Martínez A, Varadé J, Lamas JR, Fernández-Arquero M, Jover JA, de la Concha EG, Fernández-Gutiérrez B, Urcelay E. Ann Rheum Dis. 2008 Sep;67(9):1352-3. PMID: 18697781
Investigation of CD69 as a new candidate gene for rheumatoid arthritis. Rueda B, Fernandez-Gutierrez B, Balsa A, Pacual-Salcedo D, Lamas JR, Raya E, Gonzalez-Gay MA, Martin J. Tissue Antigens. 2008 Sep;72(3):206-10. Epub 2008 May 29. PMID: 18627570
Differential Proteome of Articular Chondrocytes From Patients with Osteoarthritis. Raquel Rollín, Pilar Tornero, Fernando Marco, Emilio Camafeita, Enrique Calvo, Luis López-Durán, Juan Ángel Jover, Juan Antonio López, José Ramón Lamas, Benjamín Fernández-Gutiérrez. J Proteomics Bioinform 1: 267-280.
Polymorphisms in the selenoprotein S gene: lack of association with autoimmune inflammatory diseases. Martínez A, Santiago JL, Varadé J, Márquez A, Lamas JR, Mendoza JL, de la Calle H, Díaz-Rubio M, de la Concha EG, Fernández-Gutiérrez B, Urcelay E. BMC Genomics. 2008 Jul 14;9:329. PMID: 18625033
Association of the IFIH1-GCA-KCNH7 chromosomal region with rheumatoid arthritis. Martínez A, Varadé J, Lamas JR, Fernández-Arquero M, Jover JA, de la Concha EG, Fernández-Gutiérrez B, Urcelay E. Ann Rheum Dis. 2008 Jan;67(1):137-8. No abstract available. PMID: 18077546
PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population. Martinez A, Valdivia A, Pascual-Salcedo D, Lamas JR, Fernández-Arquero M, Balsa A, Fernández-Gutiérrez B, de la Concha EG, Urcelay E. Rheumatology (Oxford). 2005 Oct;44(10):1263-6. Epub 2005 Jul 5. PMID: 15998632
Potential relationship between herpes viruses and rheumatoid arthritis: analysis with quantitative real time polymerase chain reaction. Alvarez-Lafuente R, Fernández-Gutiérrez B, de Miguel S, Jover JA, Rollin R, Loza E, Clemente D, Lamas JR. Ann Rheum Dis. 2005 Sep;64(9):1357-9. PMID: 16100341
Human parvovirus B19, varicella zoster virus, and human herpes virus 6 in temporal artery biopsy specimens of patients with giant cell arteritis: analysis with quantitative real time polymerase chain reaction. Alvarez-Lafuente R, Fernández-Gutiérrez B, Jover JA, Júdez E, Loza E, Clemente D, García-Asenjo JA, Lamas JR. Ann Rheum Dis. 2005 May;64(5):780-2. PMID: 15834059
Specific interaction of heterogeneous nuclear ribonucleoprotein A1 with the -219T allelic form modulates APOE promoter activity. Campillos M, Lamas JR, García MA, Bullido MJ, Valdivieso F, Vázquez J. Nucleic Acids Res. 2003 Jun 15;31(12):3063-70. PMID: 12799433
The peptide repertoires of HLA-B27 subtypes differentially associated to spondyloarthropathy (B*2704 and B*2706) differ by specific changes at three anchor positions. Sesma L, Montserrat V, Lamas JR, Marina A, Vázquez J, López de Castro JA. J Biol Chem. 2002 May 10;277(19):16744-9. Epub 2002 Mar 1. PMID: 11875071
Peptide presentation to an alloreactive CTL clone is modulated through multiple mechanisms involving polymorphic and conserved residues in HLA-B27. García-Peydró M, Paradela A, Lamas JR, López De Castro JA. J Immunol. 1999 Dec 1;163(11):6060-4. PMID: 10570294
Modulation at multiple anchor positions of the peptide specificity of HLA-B27 subtypes differentially associated with ankylosing spondylitis. Lamas JR, Paradela A, Roncal F, López de Castro JA. Arthritis Rheum. 1999 Sep;42(9):1975-85. PMID: 10513815
Nonapeptide analogues containing (R)-3-hydroxybutanoate and beta-homoalanine oligomers: synthesis and binding affinity to a class I major histocompatibility complex protein. Poenaru S, Lamas JR, Folkers G, López de Castro JA, Seebach D, Rognan D. J Med Chem. 1999 Jul 1;42(13):2318-31. PMID: 10395472
Structure-based design of nonnatural ligands for the HLA-B27 protein. Dédier S, Krebs S, Lamas JR, Poenaru S, Folkers G, López de Castro JA, Seebach D, Rognan D. J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):645-57. PMID: 10071790
Substituting nonpeptidic spacers for the T cell receptor-binding part of class I major histocompatibility complex-binding peptides. Krebs S, Lamas JR, Poenaru S, Folkers G, de Castro JA, Seebach D, Rognan D. J Biol Chem. 1998 Jul 24;273(30):19072-9. PMID: 9668090
Relationship between peptide binding and T cell epitope selection: a study with subtypes of HLA-B27. Lamas JR, Brooks JM, Galocha B, Rickinson AB, López de Castro JA. Int Immunol. 1998 Mar;10(3):259-66. PMID: 9576613
An HLA-B27 polymorphism (B*2710) that is critical for T-cell recognition has limited effects on peptide specificity. García F, Rognan D, Lamas JR, Marina A, López de Castro JA. Tissue Antigens. 1998 Jan;51(1):1-9. PMID: 9459498
Fine specificity of antigen binding to two class I major histocompatibility proteins (B*2705 and B*2703) differing in a single amino acid residue. Rognan D, Krebs S, Kuonen O, Lamas JR, López de Castro JA, Folkers G. J Comput Aided Mol Des. 1997 Sep;11(5):463-78. PMID: 9385550
HLA-B27 (B*2701) specificity for peptides lacking Arg2 is determined by polymorphism outside the B pocket. García F, Galocha B, Villadangos JA, Lamas JR, Albar JP, Marina A, Lópaz de Castro JA. Tissue Antigens. 1997 Jun;49(6):580-7. PMID: 9234479
Binding of peptides naturally presented by HLA-B27 to the differentially disease-associated B*2704 and B*2706 subtypes, and to mutants mimicking their polymorphism. Galocha B, Lamas JR, Villadangos JA, Albar JP, López de Castro JA. Tissue Antigens. 1996 Nov;48(5):509-18. PMID: 8988533